Department:  Faculty of Veterinary Science, Institute of Microbiology

Position:  Assistant Professor

HEC Approved Supervisor:  YES

Research Intersts:  The focus of my research is the molecular epidemiology of Clostridium perfringens in Poultry and Livestock species. Our work frequently entails the bacterial outbreak investigation using whole genome, DNA fingerprinting-based platforms such as PFGE, MLST, etc. Our expertise is in cutting-edge technologies to provide rapid and robust diagnostic solutions in food animals and research has contributed to molecular epidemiology of bacterial pathogens, particularly in unraveling the population genetic structure, evolution and virulence mechanisms of major zoonotic pathogens: Clostridium perfirngens, Salmonella enteridus, Staphylococcus aureus etc. I am member of the British Society for Antimicrobial Chemotherapy (United Kingdom).

Publications:  

1. Zafar Khan MU, Khalid S, Humza M, Yang S, Alvi MA, Munir T, Ahmad W, Iqbal MZ, Tahir MF, Liu Y and Zhang J, 2022, Infection Dynamics of Clostridium perfringens Fingerprinting in Buffalo and Cattle of Punjab Province, Pakistan, Frontier in Veterinary Sciences , 568, 77-85
2. Yang, S.; Zafar Khan, M. U [1st Equal]. Liu, B.; Humza, M.; Yin, S.; Cai, J., 2022, Potential Role In Vitro Analysis of TGF-? Signaling Modulation of Porcine Alveolar Macrophages in Porcine Circovirus Type 2b Infection.f Flavivirus NS2B-NS3 Proteases in Viral Pathogenesis and Antifla, Veterinary Sciences , 9, 101
3. Khan, M.U.Z.; Humza, M.; Yang, S.; Alvi, M.A.; Iqbal, M.Z.; Zain-ul-Fatima, H.; Khalid, S.; Munir, T.; Cai, J, 2021, Occurrence and Toxicogenetic Profiling of Clostridium perfringens in Buffalo and Cattle: An Update from Pakistan. , Toxins, 13, 212
4. Khan, M.U.Z.; Humza, M.; Yang, S.; Iqbal, M.Z.; Xu, X.; Cai, J, 2021, Evaluation and Optimization of Antibiotics Resistance Profile against Clostridium perfringens from Buffalo and Cattle in Pakistan. Antibiotics , Antibiotics , 10, 59
5. Khan MUZ, Liu B, Yang S, Xu X, Wang Y and Cai J, 2020, Genetic diversity of Clostridium perfringens strains isolated from broiler chickens revealed by PFGE analysis in China and Pakistan., Pakistan Veterinary Journal , 41, 85-91
6. Yang, S.; Liu, B.; Yin, S.; Shang, Y.; Zhang, X.; Khan, M.U.Z.; Liu, X.; Cai, J., 2020, Porcine Circovirus Type 2 Induces Single Immunoglobulin Interleukin-1 Related Receptor (SIGIRR) Down regulation to Promote Interleukin-1? Up regulation in Porcine Alveolar Macrophage., Viruses , 11, 1021
7. Yanhua Wang, Muhammad Umar Zafar Khan, Xiao Xu, and Jianping Cai, 2019, Clostridium perfringens VirS/VirR two-component system regulation mechanism, Chinese Journal of Zoonoses, 35, 934-938
8. Xiao Xu, Yanhua Wang, Muhammad Umar Zafar Khan, Jianping Cai, 2019, Development of an RPA diagnostic method for Gallus gallus for Clostridium perfringens. , Chinese Journal of Zoonoses, 49, 1475-1483

TTS

+92-41- 9200161-170: Ext 3113

03008800227

umar.zafarkhan@uaf.edu.pk